Is it dangerous to take mdma while also taking methadone?

Yes. It is dangerous to take either of these drugs. Either one can kill you. When you take both together you are taking a big risk. Mdma (ecstacy) is a stimulant that is neurotoxic and can affect cardiovascular system (heart attack, stroke) Methadone is a pure opioid that can stop your respiration or put you in a coma. Deaths from abuse/overdose of opioids is now on the rise. Please don't do it.