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What's the difference between Locoid (hydrocortisone butyrate) Lipocream and clobetasol cream?
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Dr. John Ebner
Dermatology
In brief: Potency
Locoid (hydrocortisone butyrate) lipocream is a medium/low potency topical steroid while clobetasol is a ultra-high potency topical steroid.
Clobetasol is more likely to cause side effects like skin thinning, scarring, discoloration which can all be permanent. Locoid (hydrocortisone butyrate) is much less likley to cause this. However, clobetasol is far more powerful than locoid (hydrocortisone butyrate). They are used for different conditions in different locations.

In brief: Potency
Locoid (hydrocortisone butyrate) lipocream is a medium/low potency topical steroid while clobetasol is a ultra-high potency topical steroid.
Clobetasol is more likely to cause side effects like skin thinning, scarring, discoloration which can all be permanent. Locoid (hydrocortisone butyrate) is much less likley to cause this. However, clobetasol is far more powerful than locoid (hydrocortisone butyrate). They are used for different conditions in different locations.
Dr. John Ebner
Dr. John Ebner
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