2 doctors weighed in:

How does cyclosporine damage kidney tissue bad?

2 doctors weighed in
Rohini Rao
General Practice
1 doctor agrees

In brief: Ischemia

One of the ways Cyclosporine causes kidney damage is by causing vasoconstriction of the renal vasculature, thereby reducing blood flow to the kidneys.
This results in ischemic injury.

In brief: Ischemia

One of the ways Cyclosporine causes kidney damage is by causing vasoconstriction of the renal vasculature, thereby reducing blood flow to the kidneys.
This results in ischemic injury.
Rohini Rao
Rohini Rao
Answer assisted by Rohini Rao, Medical Student
Thank
Dr. Ally-Khan Somani
Dermatology

In brief: Direct injury

Cyclosporine can cause renal dysfunction by inducing changes in blood flow within the kidney leading to decreased blood flow (ischemia).
The drug can also cause chronic injury to the filtration units in the kidney (glomerulus) and thickening (fibrosis).

In brief: Direct injury

Cyclosporine can cause renal dysfunction by inducing changes in blood flow within the kidney leading to decreased blood flow (ischemia).
The drug can also cause chronic injury to the filtration units in the kidney (glomerulus) and thickening (fibrosis).
Dr. Ally-Khan Somani
Dr. Ally-Khan Somani
Thank
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