Depends! If a patient has RA, RF will go down with traditional DMARD Rx: sulphasalazine, hydroxchloroquine, methotrexate. Humira and other TNF-a inhibitors do not!
Yes, but. Yes, but it is not a useful way to track the effectiveness of treatment of rheumatoid arthritis. To assess treatment of RA, the doctor does a tender joint count, a swollen joint count, listens to symptoms, and will occasionally do follow-up X-rays or laboratory work such as a sedimentation rate or C-reactive protein.
YES. Rheumatoid factors can change sometimes day to day and also how the test is done. It also may change with the level of disease activity.
Yes. Particularly if taking dmards. These are drugs to treat ra. Rf levels are now reported in units rather than dilutions, so big drops do occur, and a a good sign that the medication is working.
A protein in blood. Rheumatoid factor is a protein-igm- directed against another protein- igg in the blood and is seen in high frequency (>80%) of patients with rheumatoid arthritis. It is not specific for R.A. As it may be seen in other disease states a high concentration of rhuematoid factor is highly suspicious for the disease but it has to fit the patient's complaints and physical findings.
Rheumatoid factor is. An antibody that is not normally found in the blood, so your body's production of it may indicate RA or another connective tissue disease. However, it can also be present in healthy individuals with no known disease. By contrast, according to the national institutes of health, individuals with these types of diseases can have a low rheumatoid factor or none at all.
RF specifically. It is usually an immunoglobin m antibody directed against the tail portion of immunoglobin g. What tricks the body into doing this is not known.
Your question cannot. Can't answer your question. Rf of 5 tells me little. Rephrase it and i'll try again!
Variable. Several online sites to order your own cash pay which are generally cheaper than in a hospital. Reputable one is lifeextension. Com. Can google others: "online lab tests".
The higher more sign. The higher the titer of rf, the more likely it is a significant indicator of an automimmune disease, most likely ra. However it can be quite elevated in sarcoid, sjogren's, cryoglobulinemia, among others to name a few. A ccp antibody should be the next test obtained. If significantly positive, the DX is probably ra.
Antibody produced. There are plasma cells that produce antibodies. These are throughout the body and especially in the bone marrow and lymph nodes and they also circulate. They are stimulated to produce rheumatoid factor, when they are exposed to an antigen. It can also be produced in many conditions including infections, chronic illness, rheumatoid arthritis and other connective tissue diseases.
Anytime. Rheumatoid factor is a protein and may be found under various circumstances. Having a positive rheumatopid factor is not synonamous with having rheumatoid arthritis. Various protein abnormalities can procduce rheumatoid factor and it may be seen in other conditions as well.
High value. I am assuming you had the test done because you were having joint pain and if this is so, it looks as though you may have rheumatoid arthritis. Some patients with high values like you have may require more aggressive treatment for your joint disease. See a rheumatologist if not doing so already.
RF! Rheumatoid factor is present in 5% of the population, while only about 1% have rheumatoid arthritis. Rheumatoid factor is usually an igm moiety directed against the "tail" of igg! Any chronic immune stimulation, including infection, can cause a positive rf!