4 doctors weighed in:
How does prednisone affect your mood?
4 doctors weighed in

Dr. Barbara Stark Baxter
Internal Medicine - Allergy & Immunology
3 doctors agree
In brief: Euphoric grouch?
Prednisone can cause euphoria, agitation, insomnia, mania (especially in bipolar sufferers), psychosis, confusion, hunger, depression and anxiety.
Many initially feel very energetic and get a lot done, then exhausted and depressed when it is stopped. Often patients tell me they think they are fine but their families find them short-tempered. Side effects are dose and duration-related; temporary.

In brief: Euphoric grouch?
Prednisone can cause euphoria, agitation, insomnia, mania (especially in bipolar sufferers), psychosis, confusion, hunger, depression and anxiety.
Many initially feel very energetic and get a lot done, then exhausted and depressed when it is stopped. Often patients tell me they think they are fine but their families find them short-tempered. Side effects are dose and duration-related; temporary.
Dr. Barbara Stark Baxter
Dr. Barbara Stark Baxter
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