Is there a connection between anklosing spondylitis and cancer?

Complication of . Treatment. One of the treatments for ankylosing spondylitis is radiation of the affected skeleton. Radiation increases the risk of leukemia and bone tumors.
Indirectly, yes. Ankylosing spondylitis can be a manifestation of certain types of colitis that have a lifetime risk of developing colorectal cancer. Best to talk with your doctor to see if you meet these criteria.