5 doctors weighed in:

Anyone have lupus or know any information on C4 complement?

5 doctors weighed in
Dr. Michael Laccheo
Internal Medicine - Rheumatology
2 doctors agree

In brief: Low levels = bad

Rheumatologists measure c4 and c3 levels in lupus because low levels are seen in active disease.

In brief: Low levels = bad

Rheumatologists measure c4 and c3 levels in lupus because low levels are seen in active disease.
Dr. Michael Laccheo
Dr. Michael Laccheo
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Dr. Vance Harris
Family Medicine
1 doctor agrees

In brief: C4 protein

Complement c4 is a blood test that measures the activity of a certain protein that is part of the complement system. The complement system is a group of proteins that move freely through your bloodstream. The proteins work with your immune system and play a role in the development of inflammation.
This test is usually elevated in immune diseases or infections.

In brief: C4 protein

Complement c4 is a blood test that measures the activity of a certain protein that is part of the complement system. The complement system is a group of proteins that move freely through your bloodstream. The proteins work with your immune system and play a role in the development of inflammation.
This test is usually elevated in immune diseases or infections.
Dr. Vance Harris
Dr. Vance Harris
Thank
Dr. Thomas Namey
Internal Medicine - Rheumatology

In brief: C4 low?

C4 deficiency is commonly associated with sle.
Therefore in this case it does not measure activity. To assess lupus activity, other than clinical findings, i always get a c2, c4, and a c3.

In brief: C4 low?

C4 deficiency is commonly associated with sle.
Therefore in this case it does not measure activity. To assess lupus activity, other than clinical findings, i always get a c2, c4, and a c3.
Dr. Thomas Namey
Dr. Thomas Namey
Thank
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