4 doctors weighed in:
Can you please explain the significance of monoclonal alpha chain without accompanying light chain?
4 doctors weighed in

Dr. Gaston Moran Celayes
Internal Medicine
3 doctors agree
In brief: Abnormal globulin
The gammaglobulins, which are proteins that defend our body from different diseases are formed of two chains the light and the heavy chain.
In certain diseases, such as multiple myeloma, one cell starts to produce one type of (or part of) gammaglobulin. This proteins are all the same (therefore "monoclonal") and usually non-functioning. It can accumulate in tissues producing more damage.

In brief: Abnormal globulin
The gammaglobulins, which are proteins that defend our body from different diseases are formed of two chains the light and the heavy chain.
In certain diseases, such as multiple myeloma, one cell starts to produce one type of (or part of) gammaglobulin. This proteins are all the same (therefore "monoclonal") and usually non-functioning. It can accumulate in tissues producing more damage.
Dr. Gaston Moran Celayes
Dr. Gaston Moran Celayes
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