2 doctors weighed in:

Any one have a child with jra, stills disease?

2 doctors weighed in
Dr. Robert Lowe
Pediatric Rheumatology

In brief: Autoinflammatory dis

Systemic jia/jra is actually an autoinflammatory disease rather than an autoimmune disease and is more similar to periodic fever syndromes than RA or jra.
There's a problem with the innate immune system's triggering and control of inflammation, not a problem with mistakenly recognizing one's own proteins as foreign (like a virus). As such, Anakinra and steroids are most effective long term meds.

In brief: Autoinflammatory dis

Systemic jia/jra is actually an autoinflammatory disease rather than an autoimmune disease and is more similar to periodic fever syndromes than RA or jra.
There's a problem with the innate immune system's triggering and control of inflammation, not a problem with mistakenly recognizing one's own proteins as foreign (like a virus). As such, Anakinra and steroids are most effective long term meds.
Dr. Robert Lowe
Dr. Robert Lowe
Thank
Dr. Touraj Shafai
Pediatrics

In brief: Still's disease

Still's disease is the old name for sytemic onset jra, which starts with high fever and usually with no arthritis.
At times these childre have joint pain. They have high white blood cell and elevated sed. Rate. The DX in one of excluding a severe infection. Its association with hepatitis and dic was reported in ped, vol. 103. P 872, 1983. I am a co-author of this paper.

In brief: Still's disease

Still's disease is the old name for sytemic onset jra, which starts with high fever and usually with no arthritis.
At times these childre have joint pain. They have high white blood cell and elevated sed. Rate. The DX in one of excluding a severe infection. Its association with hepatitis and dic was reported in ped, vol. 103. P 872, 1983. I am a co-author of this paper.
Dr. Touraj Shafai
Dr. Touraj Shafai
Thank
1 comment
Dr. Robert Lowe
Kids will often have arthritis at the onset of systemic juvenile idiopathic arthritis (JIA) which can be quite severe. They can have low white blood cell counts, anemia and low platelets along with low (or falling) ESR which is a sign that macrophage activation syndrome is developing which is associated with elevated liver enzymes (hepatitis), and disseminated intravascular coagulation.
Get help from a real doctor now
Dr. Adam Smith
Board Certified, Internal Medicine
13 years in practice
382K people helped
Continue
108,000 doctors available
Read more answers from doctors