2 doctors weighed in:
What is inheritance and pentrance of eds?
2 doctors weighed in

Dr. Gerry Tolbert
Family Medicine
1 doctor agrees
In brief: Depends
Ehlers danlos is a family of disorders, which has 6 major and several minor types.
Given the multiple genes involved, it can be inherited in both autosomal dominant and autosomal recessive patterns, and can even spring from a de novo mutation. Penetrance depends on the type of mutation, and can therefore not be reliably calculated without more information.

In brief: Depends
Ehlers danlos is a family of disorders, which has 6 major and several minor types.
Given the multiple genes involved, it can be inherited in both autosomal dominant and autosomal recessive patterns, and can even spring from a de novo mutation. Penetrance depends on the type of mutation, and can therefore not be reliably calculated without more information.
Dr. Gerry Tolbert
Dr. Gerry Tolbert
Thank
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