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What causes tibial hemimelia?

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Dr. James Okamoto
Family Medicine

In brief: It is genetic

Tibial hemimelia syndrome (affects both legs) is believed to be due to an autosomal dominant gene passed on from one of the parents, while unilateral tibial hemimelia only affects one limb, and is believed to be due to an autosomal recessive gene, passed on by both parents.
It may also be a spontaneous gene mutation, in which neither parent passed on the gene, but it just developed spontaneously.

In brief: It is genetic

Tibial hemimelia syndrome (affects both legs) is believed to be due to an autosomal dominant gene passed on from one of the parents, while unilateral tibial hemimelia only affects one limb, and is believed to be due to an autosomal recessive gene, passed on by both parents.
It may also be a spontaneous gene mutation, in which neither parent passed on the gene, but it just developed spontaneously.
Dr. James Okamoto
Dr. James Okamoto
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