Diet and exercise not enough? What's the usual first cholesterol drug people try?

A statin. As the most prescribed drug in the world, Lipitor (or the generic equivalent atorvastatin) is the most likely drug your doctor will try. When looking at cardiovascular risk reduction, hmg coa reductase inhibitors or "statins, " offer excellent data for both efficacy and safety. It is important to remember, many lifestyle modifications and/or medication options may benefit your unique situation.