4 doctors weighed in:
Does highly elevated antinuclear antibody result always mean systemic lupus erythematosus?
4 doctors weighed in

Dr. Michael Sparacino
Family Medicine
2 doctors agree
In brief: Not always
Unfortunately, there is no single laboratory test that absolutely rules in or out systemic lupus erythematosis (sle).
Although a highly positive antinuclear antigen (ANA) is common in sle, diagnosis is based on a careful history, physical exam and laboratory evaluation.

In brief: Not always
Unfortunately, there is no single laboratory test that absolutely rules in or out systemic lupus erythematosis (sle).
Although a highly positive antinuclear antigen (ANA) is common in sle, diagnosis is based on a careful history, physical exam and laboratory evaluation.
Dr. Michael Sparacino
Dr. Michael Sparacino
Thank
Dr. John Goldman
Internal Medicine - Rheumatology
In brief: No
The presence of and anti nuclear antbody does not make a specific diagnosis no matter how high it is.
You have to integrate it into the total clinical picture. It can be seen in non-lupus settings and other tests have to be done before the diagnosis is clear.

In brief: No
The presence of and anti nuclear antbody does not make a specific diagnosis no matter how high it is.
You have to integrate it into the total clinical picture. It can be seen in non-lupus settings and other tests have to be done before the diagnosis is clear.
Dr. John Goldman
Dr. John Goldman
Thank
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