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What is the difference between infranuclear and supranuclear paralysis?

1 doctor weighed in

In brief: Different types

Supranuclear refers to loss of function due to a lack of high level cerebral control of a cranial nerve.
E.G., in supranuclear gaze paresis there is difficulty voluntarily moving the eyes, but reflex eye movements are intact. Nuclear/ infranuclear refers to problems caused by damage to a cranial nerve nucleus or nerve itself. In this case voluntary & reflex movements would be impaired.

In brief: Different types

Supranuclear refers to loss of function due to a lack of high level cerebral control of a cranial nerve.
E.G., in supranuclear gaze paresis there is difficulty voluntarily moving the eyes, but reflex eye movements are intact. Nuclear/ infranuclear refers to problems caused by damage to a cranial nerve nucleus or nerve itself. In this case voluntary & reflex movements would be impaired.
Dr. Darren Gitelman
Dr. Darren Gitelman
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