7 doctors weighed in:
How long has prograf been around for transplant patients?
7 doctors weighed in

Dr. George Loss
Surgery - Transplant
5 doctors agree
In brief: Widely since 1994
Prograf or tacrolimus or fk-506 is a 23-membered macrolide lactone discovered in 1984 from the fermentation broth of a japanese soil sample that contained the bacteria streptomyces tsukubaensis.
It was approved by the fda as an immunosuppressant for liver transplanation in 1994 and is now approved for all solid organ transplants.

In brief: Widely since 1994
Prograf or tacrolimus or fk-506 is a 23-membered macrolide lactone discovered in 1984 from the fermentation broth of a japanese soil sample that contained the bacteria streptomyces tsukubaensis.
It was approved by the fda as an immunosuppressant for liver transplanation in 1994 and is now approved for all solid organ transplants.
Dr. George Loss
Dr. George Loss
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In brief: Over 20 years
Trials of the drug in the us started in the late 80s.
It was fda approved for kidney transplant in the 1990s.

In brief: Over 20 years
Trials of the drug in the us started in the late 80s.
It was fda approved for kidney transplant in the 1990s.
Dr. Stuart Flechner
Dr. Stuart Flechner
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