How does celiac disease affect the small intestine?

Food malabsorption. Celiac disease leads to inflammation and damage of the lining of the small intestine, which causes decreased absorption of nutrients, vitamins, iron, etc... The intestinal lining loses its microscopic "villi", which are tiny protrusions that maximize the absorptive surface area needed to absorb nutrients. A patient gets diarrhea, anemia, lactose intolerance, tummy aches, irritable bowels, etc...
Celiac. Celiac is a loss of the enzymes that break down gluten. Over time there can be inflammation and irritation to the lining of the small bowel but this is minor especially if gluten is avoided.

Related Questions

I had a biopsy of my small intestine come back with elevated lymphocytes and all the blood came back negative for celiac disease. What r other reasons?

Need more info. The hall mark of celiac disease is destruction of the lining of the intestine (mucosal atrophy). To give you a better idea about what is going on i would need a complete report of the biopsy and description of your symptoms. Read more...

Can a small bowel series diagnose Chrone's, Gastroparesis and Dumping syndrome? I know celiac disease has a blood test but it is a possible also.

No. Some pattern in small bowel series may point to certain disease entities but the ultimate diagnosis often depends on the history, the symptoms, and biopsy findings. In fact, there is no one single test which can by itself diagnose a disease condition. Read more...

I have celiac disease and am about 20 pounds underweight. I am gluten and dairy free but remain severly thin. Will my intestines heal at my age of 54?

See below. For celiac disease, the intestines completely heal in the absence of gluten (95% of the time). In 5%, however, enteropathy is refractory to gluten avoidance and may be caused by underlying immune dysregulation (constitutive IL-15 production by epithelial cells for example). Other potential causes for difficulty in gaining weight should be considered too. To begin, an EGD needs to be repeated soon. Read more...
Should. If you are truly gluten free & continue to have random IBSD episodes you may want further blood studies to look at cross reacting foods. The disorder is occasionally aggravated by food reactions that are not gluten. Items as diverse as Egg, coffee, cow milk may form IgA antibodies that may need to be eliminated from a diet for improvement to occur. A variety of labs like Cyrex (Phoenix) do these. Read more...

Is there any relation between ibd and celiac disease? How is celiac diagnosed? (since I think colonoscopy is for large intestine only?)

Yes. There is a relation, one autoimmune disease can cause another to occur. To be tested for celiac, there are blood tests and a upper intestinal biopsy of the small intestines performed by a gastroenterologist. Read more...
Similar symptoms. Ibd and celiac disease have been reported together in some patients. Some patients with ibd have also reported a relapse in symptoms on gluten free diet, but a direct relationship has not been definitively established. Celiac disease is diagnosed with the combination of upper endoscopy, duodenum (small intestine) biopsy, and blood test for celiac antibodies. Read more...

Can you please describe the differences in symptoms between irritable bowel syndrome and celiac disease?

Very similar. Symptoms of ibs and celiac's disease are very similar. The diagnosis of ibs is a diagnosis of exclusion (ie the doctor has ruled out any other diseases that have similar symptoms). Consult with your doctor to determine if a celiac work-up might be appropriate if has not all ready been done. Read more...