Donor sperm closest. No treatment for male or female infertility is 100% guaranteed, but donor sperm is the closest thing for azoospermia as it's from healthy men without fertility issues. Many men with azoospermia can have children using surgically retrieved epididymal or testicular sperm, combined with ivf with icsi. A genetic test identifies some who won't get sperm at retrieval. Donor sperm backup is a good idea.