What is a sentinel node biopsy?

Biopsy of lymph node. Lymph nodes are biopsied to see if cancer has spread beyond the primary site. Using a radioactive tracer and dye, the lymph nodes closest to a tumor can be identified and biopsied without having to remove all the potential draining nodes which can lead to complications. Most often done with breast cancer and melanoma.

Related Questions

What is a sentinel node biopsy procedure?

Sentinel node. Your surgeon will give a dye to look for these mother node or sentinel node, if they are negative then they don't have to look for whole nodal area. Usually biopsies in case of breast cancer or melanoma. Read more...
Sentinel node. Injecting a dye, it initially goes to mother nodes or sentinel nodes and from there nurse to whole node basin. Biopsy of these mother nodes save to biopsy or removing whole nodal areas if sentinel node negative. Read more...

What is the difference between a regular node biopsy and a sentinel node biopsy?

Little difference. Think of a lymph node as a small filter. All lymph nodes act as filters. However, certain lymph nodes are the very first filters in line- they are called sentinel lymph nodes. The idea is that if the sentinel node is removed and negative, the chances of other lymph nodes further down the line being positive is small. You take out less nodes and have less complications! Read more...

What is the difference between a needle directed biopsy and a sentinel node biopsy?

Size. A needle-directed biopsy means a hollow needle is stuck into a tumor or lymph node, and only the amount of tissue that fits inside the needle is removed. A sentinel node biopsy removes several lymph nodes entirely and the entire lymph node is examined under the microscope. A sentinel node biopsy requires an injection ahead of time to see which nodes are first in the chain of lymph nodes. Read more...
Anesthesia. A needle biopsy is performed when we have found an abnormality and want to determine whether it is cancerous or not; it is performed under local anesthesia in a doctor's office or breast center. A sentinel node biopsy is a surgical procedure to determine if a cancer has 'spread' to the lymph nodes; this information is used to stage the cancer, to guide subsequent therapy. Read more...
Diagnos vs staging. A "needle directed biopsy" is likely being used to establish a diagnosis (benign or malignant). A sentinel node biopsy is part of the pathologic staging process once a malignant diagnosis has already been established. Read more...

What is the definition or description of: sentinel node biopsy?

Metastatic node. It is first node to which lymphatic drainage and metastasis from a cancer goes to. A biopsy is a procedure that removes a small piece of living tissue from your body. The tissue is examined with a microscope for signs of damage or disease. Biopsies can be done on all parts of the body. A biopsy is the only test that can tell for sure if a suspicious area is cancer. Read more...
Sample lymph nodes. This is a surgical procedure used to evaluate the lymph nodes under the arm. A radioactive tracer and/or blue dye is injected into the breast prior to surgery. These substances travel to the lymph nodes so the surgeon can see them. He/she takes out one to four (on average) lymph nodes to see if cancer has spread. The benefit is a decrease in risk of lymphedema of the arm. Read more...

Should axillary sentinel node biopsy be done after chemotherapy?

Usually before. Sentinel lymph node biopsy is usually done at the time of lumpectomy for breast cancer. The information gained is used in the decision making as to whether adjuvant chemotherapy should be given to increase the likelihood of cure. Rarely, it might be done after chemotherapy if the initial role of chemo was to shrink the tumor to allow surgery (neoadjuvant chemotherapy). Read more...

Will the radioactive dye for sentinel node biopsy make me sick?

No. There is very little radiation with esentinel node biopsy which does not exhibit any systemic side effects. But since you are usually undergoing general anesthesia, there may be some sickness after surgery due to the anesthesia. Read more...
No. The tracer is technitium sulfa colloid. Unless one has an allergic reaction is it innocuous. Read more...
No. The dose of radiation is so low that preganant women scrub on these cases routinely. Read more...