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Can you explain acute tubular necrosis?

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Dr. Jason Hemming
Internal Medicine - Gastroenterology

In brief: Ischemia, drugs

Acute tubular necrosis (atn) can happen if the kidney has severely reduced blood supply (ischemia).
This could be caused by hypotension (very low blood pressure), volume depletion (as a result of illness or trauma), problems with the blood vessels supplying the kidneys (renal artery blockage), and drugs that affect the flow of blood to the kidneys. Drugs and toxins can also directly cause atn.

In brief: Ischemia, drugs

Acute tubular necrosis (atn) can happen if the kidney has severely reduced blood supply (ischemia).
This could be caused by hypotension (very low blood pressure), volume depletion (as a result of illness or trauma), problems with the blood vessels supplying the kidneys (renal artery blockage), and drugs that affect the flow of blood to the kidneys. Drugs and toxins can also directly cause atn.
Dr. Jason Hemming
Dr. Jason Hemming
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