8 doctors weighed in:

I'm er+ pr- and her2+, but been told I have triple negative breast cancer. What is that?

8 doctors weighed in
Dr. Sean Canale
Breast Surgery
5 doctors agree

In brief: Mixed info

Triple negative refers to the phenotype that is er neg.
Pr neg. And her2 neg. These are usually treated with the addition of chemo often upfront to determine which are chemo sensitive (often very much so) and which are resistant (poorer prognosis). Talk with your doctor and perhaps ask to see your path report if still unsure.

In brief: Mixed info

Triple negative refers to the phenotype that is er neg.
Pr neg. And her2 neg. These are usually treated with the addition of chemo often upfront to determine which are chemo sensitive (often very much so) and which are resistant (poorer prognosis). Talk with your doctor and perhaps ask to see your path report if still unsure.
Dr. Sean Canale
Dr. Sean Canale
Thank
Dr. Andrew Turrisi
Radiation Oncology
2 doctors agree

In brief: Someone is

Mis-informed: er, pr, her-2-neu all negative is triple negative; you report you are dually positive with 2 receptors.
Have your medical oncologist check and re-explain this 2 u. You hae every reason to be quite optimistic, but your med onc has more factsthan i do. Best wishes.

In brief: Someone is

Mis-informed: er, pr, her-2-neu all negative is triple negative; you report you are dually positive with 2 receptors.
Have your medical oncologist check and re-explain this 2 u. You hae every reason to be quite optimistic, but your med onc has more factsthan i do. Best wishes.
Dr. Andrew Turrisi
Dr. Andrew Turrisi
Thank
Dr. Barry Kahn
Pathology

In brief: Clarification needed

Triple negative breast cancer refers to breast cancers that have tested negative for estrogen receptor protein (er), Progesterone receptor protein (pr) and her-2/neu.
They tend to be more aggressive tumors. From your description, your tumor is positive for er and her2, which opens up several treatment options that "triple negative" patients don't have. Clarify your status with your oncologist.

In brief: Clarification needed

Triple negative breast cancer refers to breast cancers that have tested negative for estrogen receptor protein (er), Progesterone receptor protein (pr) and her-2/neu.
They tend to be more aggressive tumors. From your description, your tumor is positive for er and her2, which opens up several treatment options that "triple negative" patients don't have. Clarify your status with your oncologist.
Dr. Barry Kahn
Dr. Barry Kahn
Thank
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