When did alpha fetoprotein testing start?

1980's. The Alpha fetoprotein test was around when i was a resident physician. The test has progressed through the y ears such that there are four levels measured in the pregnant woman's blood looking for the risk of down's syndrome (trisomy 21), trisomy 18 & neural tube defects like spina bifida. This is called the quadruple screen best measured between 16 & weeks of pregnancy.

Related Questions

Please exlain alpha-fetoprotein testing for genetic disorders?

Alpha fetal protein. AFP is a fetal specific globulin, synthesized by the fetal yolk sac, gastrointestinal tract, and liver. The function of AFP is unknown. AFP blood levels can be measured during the second trimester to screen for open spina bifida and anencephaly, but can also uncover fetal abnormalities such as abdominal wall defects. AFP is also used in screening tests for downs syndrome and edwards syndrome. Read more...

Testing in pregnancy showed elevated alpha-fetoprotein. What does it mean?

Alpha feto protein. An elevation of Alpha feto protein between 15-18 weeks in pregnancy may be asign of a defect in the forming fetal spine( neural tubr defect). It requires a specialized ultrasound imaging to rule out the above possibility. You must speak with your doctor and seek adequate care. Read more...