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Please exlain alpha-fetoprotein testing for genetic disorders?

3 doctors weighed in
Dr. Henry Garcia
Obstetrics & Gynecology
2 doctors agree

In brief: Alpha fetal protein

AFP is a fetal specific globulin, synthesized by the fetal yolk sac, gastrointestinal tract, and liver. The function of AFP is unknown.
AFP blood levels can be measured during the second trimester to screen for open spina bifida and anencephaly, but can also uncover fetal abnormalities such as abdominal wall defects. AFP is also used in screening tests for downs syndrome and edwards syndrome.

In brief: Alpha fetal protein

AFP is a fetal specific globulin, synthesized by the fetal yolk sac, gastrointestinal tract, and liver. The function of AFP is unknown.
AFP blood levels can be measured during the second trimester to screen for open spina bifida and anencephaly, but can also uncover fetal abnormalities such as abdominal wall defects. AFP is also used in screening tests for downs syndrome and edwards syndrome.
Dr. Henry Garcia
Dr. Henry Garcia
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