2 doctors weighed in:
Can you explain mosaic turner syndrome?
2 doctors weighed in

Dr. James Ferguson
Pediatrics
In brief: Timing of error
At conception , the embryo begin duplicating the chromosomes (chms) donated by egg & sperm to form the 23 chromosome pairs.
If one x chm didn't make it , you will only have a turner pattern (45 chms xo) . If a normal xx pattern starts but an x is lost after several divisions the mosaic is created by having one normal 46xx & another 45xo cell lines replicating throughput the body.

In brief: Timing of error
At conception , the embryo begin duplicating the chromosomes (chms) donated by egg & sperm to form the 23 chromosome pairs.
If one x chm didn't make it , you will only have a turner pattern (45 chms xo) . If a normal xx pattern starts but an x is lost after several divisions the mosaic is created by having one normal 46xx & another 45xo cell lines replicating throughput the body.
Dr. James Ferguson
Dr. James Ferguson
Thank
Dr. David Galbraith
Pediatrics
In brief: A little complex
Classic turner syndrome is a female who is missing 1 of the 2 x chromosomes, designated as 46x.
A normal female has 2 x chromosomes (46xx). Most turner mosaics have a mix of normal cells and turner cells resulting in a milder form of turner syndrome. There are several variations however-- some with 1 normal and one abnormal x chromosomes and evan a male form with a normal x and an abnormal y.

In brief: A little complex
Classic turner syndrome is a female who is missing 1 of the 2 x chromosomes, designated as 46x.
A normal female has 2 x chromosomes (46xx). Most turner mosaics have a mix of normal cells and turner cells resulting in a milder form of turner syndrome. There are several variations however-- some with 1 normal and one abnormal x chromosomes and evan a male form with a normal x and an abnormal y.
Dr. David Galbraith
Dr. David Galbraith
Thank
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