7 doctors weighed in:

Do ADHD medications target norepinephrine?

7 doctors weighed in
Dr. R Sangal
Internal Medicine - Sleep Medicine
5 doctors agree

In brief: Depends on the med

It depends on the medicine.
Amphetamines and methylphenidate work predominantly on dopamine, but also on norepinephrine. Atomoxetine works selectively on norepinephrine, as does guanfacine. Off-label medicines such as Imipramine and bupropion have effects on several brain chemicals (imipramine may work on norepinephrine, acetylcholine, histamine).

In brief: Depends on the med

It depends on the medicine.
Amphetamines and methylphenidate work predominantly on dopamine, but also on norepinephrine. Atomoxetine works selectively on norepinephrine, as does guanfacine. Off-label medicines such as Imipramine and bupropion have effects on several brain chemicals (imipramine may work on norepinephrine, acetylcholine, histamine).
Dr. R Sangal
Dr. R Sangal
Thank
Dr. Alfredo Soto
Psychiatry
1 doctor agrees

In brief: Yes

Most, if not all, medications shown to help adhd have been associated with effects on norepinephrine.
Many also target Dopamine receptors.

In brief: Yes

Most, if not all, medications shown to help adhd have been associated with effects on norepinephrine.
Many also target Dopamine receptors.
Dr. Alfredo Soto
Dr. Alfredo Soto
Thank
Dr. Carla Enriquez
Pediatrics

In brief: Yes

Norepinephrine (ne) is produced by brain cells to send through a connection called a "synapse" to contact another brain cell with its information bits.
Adhd meds target increased production in the sending cell, or blockage of breakdown at the receiving cell. By so doing, the normal cell information lasts longer to allow for better connectivity between neurons.

In brief: Yes

Norepinephrine (ne) is produced by brain cells to send through a connection called a "synapse" to contact another brain cell with its information bits.
Adhd meds target increased production in the sending cell, or blockage of breakdown at the receiving cell. By so doing, the normal cell information lasts longer to allow for better connectivity between neurons.
Dr. Carla Enriquez
Dr. Carla Enriquez
Thank
Get help from a real doctor now
Dr. Cindy Juster
Board Certified, Pediatrics
32 years in practice
2M people helped
Continue
108,000 doctors available
Read more answers from doctors