3 doctors weighed in:
Will someone get hives from oxycodone if they get hives from vicodin?
3 doctors weighed in

Dr. Barbara Stark Baxter
Internal Medicine - Allergy & Immunology
1 doctor agrees
In brief: YES, probably
Different opioids have different abilities to stimulate mast cells to release histamine, the substance that causes the skin to make wheals, or hives.
These reactions are not allergies, meaning you do not need prior exposure and antibody production in order to react. Oxycodone is a low histamine releaser vs codeine, though. http://depts.washington.edu/druginfo/dtt/2006_vol35_files/v35n4.pdf.

In brief: YES, probably
Different opioids have different abilities to stimulate mast cells to release histamine, the substance that causes the skin to make wheals, or hives.
These reactions are not allergies, meaning you do not need prior exposure and antibody production in order to react. Oxycodone is a low histamine releaser vs codeine, though. http://depts.washington.edu/druginfo/dtt/2006_vol35_files/v35n4.pdf.
Dr. Barbara Stark Baxter
Dr. Barbara Stark Baxter
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Dr. Yash Khanna
Family Medicine
In brief: Allergy to oxy/vicod
It is unlikely as oxycodone and hydrcodone the med in vicodin are both different synthetic compounds, and vicodin also contains acitamnophen and hives may be from that as well.

In brief: Allergy to oxy/vicod
It is unlikely as oxycodone and hydrcodone the med in vicodin are both different synthetic compounds, and vicodin also contains acitamnophen and hives may be from that as well.
Dr. Yash Khanna
Dr. Yash Khanna
Thank
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