3 doctors weighed in:

Which local injectable anesthetic has the longest duration?

3 doctors weighed in
Dr. Karen Sibert
Anesthesiology
1 doctor agrees

In brief: Bupivacaine

Bupivacaine (marcaine, sensorcaine) is the longest-acting local anesthetic.
Adding Epinephrine to it can make the duration even longer. Exactly how long it will last in an individual is hard to predict. It also makes a difference whether it is injected locally into an area or used in a nerve block, spinal anesthesia, or epidural anesthesia.

In brief: Bupivacaine

Bupivacaine (marcaine, sensorcaine) is the longest-acting local anesthetic.
Adding Epinephrine to it can make the duration even longer. Exactly how long it will last in an individual is hard to predict. It also makes a difference whether it is injected locally into an area or used in a nerve block, spinal anesthesia, or epidural anesthesia.
Dr. Karen Sibert
Dr. Karen Sibert
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1 comment
Dr. Mark Gujer
A new local anesthetic has hit the market called Exparel. It can be used on sensory nerves currently and last for about 3 days. Works great for inguinal hernia repairs and foot surgery.
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