PSP. Progressive supranuclear palsy: the disorder's long name indicates that the disease begins slowly and continues to get worse (progressive), and causes weakness (palsy) by damaging certain parts of the brain above pea-sized structures called nuclei that control eye movements (supranuclear). It is central; demyelinating conditions occur in the peripheral nervous system.
No, tau protein. No, tau protein deposits & neurofibrillary tangles in neurons cause the death of these cells. Because they are in some similar areas as parkinson's disease, psp can appear similar clinically, but there are clear differences. Treatment approaches are roughly the same with different areas needing most attention. Primarily balance/falls/injury, did inhibiting dementia & dysphagia/aspiration.