2 doctors weighed in:

Is hyperpigmentation a part of hypopituitarism?

2 doctors weighed in
Dr. Vered Lewy-Weiss
Pediatrics - Endocrinology

In brief: No

Patients with primary adrenal insufficiency become hyper pigmented prior to diagnosis because of really high pituitary production of acth and msh (causes bronzing).
Hypopit patients can't make acth, therefore no significant msh. Bronzing is not seen in hypopit patients with secondary adrenal insufficiency.

In brief: No

Patients with primary adrenal insufficiency become hyper pigmented prior to diagnosis because of really high pituitary production of acth and msh (causes bronzing).
Hypopit patients can't make acth, therefore no significant msh. Bronzing is not seen in hypopit patients with secondary adrenal insufficiency.
Dr. Vered Lewy-Weiss
Dr. Vered Lewy-Weiss
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Dr. Cayce Jehaimi
Pediatrics - Endocrinology

In brief: No

Not typically as hyperpigmentation if due to adrenal insufficiency, is because there is increased acth hormone signaling.
This latter hormone is often missing in individuals with steroid dependent hypopituitarism.

In brief: No

Not typically as hyperpigmentation if due to adrenal insufficiency, is because there is increased acth hormone signaling.
This latter hormone is often missing in individuals with steroid dependent hypopituitarism.
Dr. Cayce Jehaimi
Dr. Cayce Jehaimi
Thank
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