6 doctors weighed in:

What are the causes of endometriosis to develop into cancer?

6 doctors weighed in
Ben Ferguson
Surgery
3 doctors agree

In brief: Two theories.

Endometriosis is most strongly linked to ovarian cancer.
One theory for this association is that there are common risk factors for endometriosis and ovarian cancer to co-occur. The other is that endometrial cells that have spread from the uterus to the ovary can transform into cancer cells via gene mutation. However, it is generally thought that endometriosis is not a direct precursor to cancer.

In brief: Two theories.

Endometriosis is most strongly linked to ovarian cancer.
One theory for this association is that there are common risk factors for endometriosis and ovarian cancer to co-occur. The other is that endometrial cells that have spread from the uterus to the ovary can transform into cancer cells via gene mutation. However, it is generally thought that endometriosis is not a direct precursor to cancer.
Ben Ferguson
Ben Ferguson
Answer assisted by Ben Ferguson, Medical Student
Thank
Dr. Gerard Honore
Fertility Medicine
1 doctor agrees

In brief: Tricky question

Experts don't agree if progression of endometriosis to cancer happens or not.
It's tricky to design studies to answer this, and simply finding endometriosis with cancer in a patient emphatically do not prove one came from the other. If progression occurs it is an infrequent phenomenon. Many assume progression may be from estrogen exposures, but this is also just speculation.

In brief: Tricky question

Experts don't agree if progression of endometriosis to cancer happens or not.
It's tricky to design studies to answer this, and simply finding endometriosis with cancer in a patient emphatically do not prove one came from the other. If progression occurs it is an infrequent phenomenon. Many assume progression may be from estrogen exposures, but this is also just speculation.
Dr. Gerard Honore
Dr. Gerard Honore
Thank
Get help from a real doctor now
Dr. Buck Parker
Board Certified, Surgery
13 years in practice
467K people helped
Continue
108,000 doctors available
Read more answers from doctors