What has to match between a donor and recipient for a bone marrow transplant to be successful?

Tissue type. The tissue type of the recipient and donor must match. This is a measurement of the hla type which looks at proteins on the surface of our cells that help the immune system recognize 'self' verus 'non-self.'.
(HLA) An essential component of allogeneic transplantation is to identify a human leukocyte antigens (hla)-matched bone marrow donor. Ideally, a brother, sister or possibly another family member can serve as the bone marrow donor. However, many patients do not have a suitable family member to serve as a donor.

Related Questions

What exactly does it mean to have a match between a donor and receipitant for a bone marrow transplant to be sucessful?

The Tissue types. There is a tissue match called hla matching which is done to check and match your tissue types with the receving person's tissue type. Read more...

Is a bone marrow transplant going to pass on donor characteristics like hair color?

Yes and no. Hair loss is common after receiving cancer treatments including bone marrow transplant. When the hair grow back, they are often of different color and texture(may turn curly!). It is not due to bone marrow itself but due to chemotherapy (and due to whole body radiotherapy, which is sometimes added to chemotherapy treatments). Read more...

How do you become a donor for bone marrow transplant?

Donor registry . Open these links: www.Marrow.Org; www. Nmdp.Org; www.Abmdr.Org; www.Dkmsamericas.Org; www.Giftoflife.Org; moremarrowdonor.Org. Read more...
Join the registry. The major registry in the us is the nmdp. They have information at bethematch.Org. Joining this registry can be done by submitting a sample (cheek swab). Then when a request from a doctor comes to the nmdp for a bone marrow transplant comes through, your information will be included in the search. If you are closely matched, they will contact you about additional testing. Read more...

How do you choose a donor for bone marrow transplant?

Matching is key. Stem cell donors are chosen based on their genetic similarity to the recipient. Hla (human leukocyte antigen) markers are profiled to test whether a particular donor would be a good match for a particular recipient. Matching hla markers is important to help avoid complications to the transplant maneuver. More details are here: http://bit.Ly/ws3r3v. Read more...

What risks are associated with bone marrow transplant as a donor?

Hardly any risks. The donor has to spare the time it takes to give blood samples for matching and tissue typing. Then you can give stem cells either from your blood(you will need to go to a blood bank like you go to give blood) or they may prefer taking your bone marrow from the hip bones...A procedure which requires you to be placed under general anasthesia for a couple of hours. There is but a minmal risk . Read more...
Nothing major. Long term no major side effects Short term bone pain, need for a line , some cases splenic rupture, basically will feel like a bad case of flu. bone marrow donors have to go to OR and have the risk of anesthesia and may need blood transfusion. Their own blood can be stored in advanced to avoid this risk . Read more...

Why are umbilical cord stem cells sometimes uses along with donor cells in an allogeneic bone marrow transplant?

One of the other. Stem cells can be obtained from 3 different sources: from Bone marrow of the Donor, blood of the donor or stem cells from umbilical cord. But we have to give an adequate number(Dose) of stem cells in order to have full protection. So combining them may only be needed because of inadequate number of stem cells from one of the sources. Read more...

How to find out if your a bone marrow match to. Someone. How do they do the bone marraow transplant for donor and one who. Needs it?

It is simple process. You can get this information on the internet by looking up: 'be the match'. Your local blood bank can also give you literature in case you do not have access to the internet. You can be a donor by volunteering, giving a sample of your inner cheek cells(they take a swab) and enter your data in the marrow bank, then call you when your cells match with a needy person. Read more...