When in leukemia can a bone marrow transplant be helpful?

Any time. We have learned that offering a transplant earlier, when a patient does not respond to therapy or has a relapse is better because there are less complications but at times this may be the only option left. If your doctors and specifically the stem cell transplant team feel this is the best option, they will offer a transplant for your disease.
Depends on leukemia . AML poor Cytogenetics or lack of response ALL poor Cytogenetics , older age CML compliant patient not able to tolerate most of frontline therapies or has refractory progressive disease CLL poor Cytogenetics and / or lack of response to therapy.
In remission is best. The 'time' is not absolute. If transplant is considered appropriate for a patient, we'd prefer the patient to be in remission or with only a minimal amount of disease at the time we start. In some cases this means we recommend a transplant within a year of diagnosis, however in other instances it is appropriate to wait many years before the risk of bmt is appropriate.

Related Questions

How far along in leukemia can a bone marrow transplant be helpful?

Balancing act. Certainly one wants to try standard therapy first in most cases because it has less complications. If this approach is unsuccessful or the patient is very high risk, transplant is considered. The decision to go forward is complicated by such things as the patient's performance status, their prior treatments and the amount of disease. These way into the final decision of when it can be helpful. Read more...
It depends. There is no one answer. It depends on the type of leukemia, patient's age etc. Read more...

How often does a bone marrow transplant not help with leukemia?

It depends. The risk of relapse depends on a number of factors, such as whether the patient is in remission, the type of leukemia, and pre-transplant prognostic factors. It also depends upon whether the transplant is autologous (from themselves as donor) or allogeneic (from someone else). The relapse risk can be from modest to almost certain depending on these factors. Read more...
It varies. The specific subtype of leukemia, remission status at start of transplant, type of donor, type of chemotherapy or radiation used for the transplant are just a few things that are needed to help assess the outcomes... The long term survivals are 20-75% depending on these and other factors. Read more...

Is a bone marrow transplant the main cure for leukemia?

Sometimes. Bone marrow transplant is a difficult treatment, but it can cure leukemia. It is important that the leukemia is in remission prior to transplant. Read more...

How often does a bone marrow transplant not work, and the leukemia cells come back?

Please give more inf. Depends on many factors including the type of leukemia, age, type of transplant. A more specific question would be easier to give an adequate response. In general allogeneic transplants for AML in remission usually have a leukemia free relapse rate of greater than 50%. Read more...
Variable. The success and failure rate of a bone marrow transplant is dependent on factors such as the type of leukemia, prior therapies the patient has had, type of transplant, and the number of times the leukemia has relapsed in the past. Please ask the question again with more details. Read more...
Depends,.... The specific leukemia, remission status at transplant, chemo/radiation used to do the transplant etc all must be considered to provide more information on this issue. Read more...

How often does a bone marrow transplant not get rid of the leukemia?

Depends. The type of leukemia (acute vs chronic, myeloid vs lymphoid), the type of bone marrow transplant (allogeneic vs autologous), the status of the leukemia (complete remission, first remission, second remission, partial remission, etc.) all affect the success of a bone marrow transplant. Read more...
Variable. The success rate of a transplant is dependent on many factors: the type of leukemia, some genetic factors about the leukemia, current remission status, prior therapies, type of transplant and other medical problems of the patient. Read more...

What occurs after a bone marrow transplant is needed for chronic myeloid leukemia?

Hopefully cure. CML is a major success story. About 30 years ago up until about 2000, the standard for cure was allogeneic bone marrow transplantation. Now, new drugs can achieve long term remissions of a decade or more. This is the new standard of care but despite this, when these drugs fail, bone marrow transplant is still the gold standard and still the only curative therapy. There are many complications. Read more...
Long recovery period. Depending on your condition, your donor match etc, you will likely be seen daily for a few months at the transplant center for close care, watching for infections, guarding against transplant effects, ensuring nutrition and exerecise improve. The ibmtr website and lls websites have good patient information available for this. Read more...
Long process. The first critical steps are donor finalization, transplant chemo followed by stem cell transplant. After this, recovery starts and first 100 days are important for infections, marrow recovery, potential graft vs host disease, and other complications. Gradually, immunesuppressive meds and then antibiotics are withdrawn. Booster vaccines are done from 12 mths onwards and follow up is for 5 yrs. Read more...