Timing is everything
Lytic therapy for strokes has been effective both IV and direct infusion in the cerebral artery.
The sooner the better. The pts who are not excluded for bleeding risk or allergies
etc.Should be treates asap. Pts within first 1-2 hrs do the best. 2-3 hrs have modest recovery and after 3 hrs prob not going to get a clinically significant improvement. Ofcourse each pt is has his own risk vs benefit.