Will penile sclerosing lymphangitis resolve on its own?

No. Lymphatic channels that become inflamed and undergo scarring or sclerosis will not heal or return to their normal state. However, the progression of sclerosing lymphangitis is unpredictable, and it may stop progressing without any intervention. Alternative routes for lymph may be established, and the damage limited. Progression is always a risk, however. Most recommend avoiding local irritation.