I suddenly have an overwhelming urge to clean house. Could it have anything to do with the tedious work I am asked to do?

Change. It could. After my first year of medical school, i went to parachutte school. Why? Because my brain needed a break and my body needed more exercize. When you do the same things repeatedly, adding in other types of activities can help to prevent boredom and can help to restore balance. If your work is tedious - recommend that you change things up every once in a while.