2 doctors weighed in:
Can I take ibuprofen while on asacol (mesalamine) hd? I am not allergic to either one.
2 doctors weighed in

Dr. Ralph Morgan Lewis
Family Medicine
In brief: Yes
No significant interactions have been reported between Asacol hd & ibuprofen.
Avoid using another salicylate (aspirin, peptobismol) in place of Ibuprofen (could lead to salicylate toxicity). Do not take antacids, acid blockers like Zantac (ranitidine) family or Prilosec family at same time as Asacol as they may decrease its effectiveness.

In brief: Yes
No significant interactions have been reported between Asacol hd & ibuprofen.
Avoid using another salicylate (aspirin, peptobismol) in place of Ibuprofen (could lead to salicylate toxicity). Do not take antacids, acid blockers like Zantac (ranitidine) family or Prilosec family at same time as Asacol as they may decrease its effectiveness.
Dr. Ralph Morgan Lewis
Dr. Ralph Morgan Lewis
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Dr. Appaji Gondi
Internal Medicine - Allergy & Immunology
In brief: May affect kidneys
Both the medications are known to adversely effect kidney function in some individuals and taking them together may have additive toxic effects on the kidneys.
However you may be able to tolerate low doses of Ibuprofen for a short period if your kidney function is normal prior to receiving these drugs. Ibuprofen and other NSAID medications can also irritate the GI tract and rarely cause bleeding.

In brief: May affect kidneys
Both the medications are known to adversely effect kidney function in some individuals and taking them together may have additive toxic effects on the kidneys.
However you may be able to tolerate low doses of Ibuprofen for a short period if your kidney function is normal prior to receiving these drugs. Ibuprofen and other NSAID medications can also irritate the GI tract and rarely cause bleeding.
Dr. Appaji Gondi
Dr. Appaji Gondi
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