4 doctors weighed in:

What can we expect from a stage 4 lung cancer patient with bone metastases- what can be done in case all treatments are ruled out?

4 doctors weighed in
Dr. Michael Thompson
Internal Medicine - Hematology & Oncology
2 doctors agree

In brief: Biomarkers in lungCA

For stage 4 non-small cell lung cancer -- specifically adenocarincoma -- i would check the biomarkers alk and egfr. The response rate with oral drugs for those targets is ~80% vs.
20% with chemo. Bone mets can be treated with bisphosphonate (zometa) or Denosumab (xgeva). Palliative care provided early has a survival benefit. Ref: temel et al. Nejm http://www.Nejm.Org/doi/pdf/10.1056/nejmoa1000678.

In brief: Biomarkers in lungCA

For stage 4 non-small cell lung cancer -- specifically adenocarincoma -- i would check the biomarkers alk and egfr. The response rate with oral drugs for those targets is ~80% vs.
20% with chemo. Bone mets can be treated with bisphosphonate (zometa) or Denosumab (xgeva). Palliative care provided early has a survival benefit. Ref: temel et al. Nejm http://www.Nejm.Org/doi/pdf/10.1056/nejmoa1000678.
Dr. Michael Thompson
Dr. Michael Thompson
Thank
Dr. Thomas Birdas
Surgery - Thoracic
1 doctor agrees

In brief: Hospice

Palliative of pain and comfort care only.

In brief: Hospice

Palliative of pain and comfort care only.
Dr. Thomas Birdas
Dr. Thomas Birdas
Thank
1 comment
Dr. Michael Thompson
Chemotherapy or newer "targeted" therapy can have a survival benefit in metastatic lung cancer. Recommending "comfort care only" universally is not appropriate. It may be appropriate for an individual patient.
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Dr. Arnon Rubin
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