2 doctors weighed in:

Has anyone tried anti-tnf drugs for RA without using methotrexate at the same time?

2 doctors weighed in
Dr. Pierre Moeser
Internal Medicine - Rheumatology
1 doctor agrees

In brief: Yes

Though the drug studies were set up to have these tnf agents used in combination with Methotrexate (mtx), many patients do take tnf agents without mtx.
Certain tnf agents work better than others if mtx is not being taken. Speak to your rheumatologist if you are considering going off mtx.

In brief: Yes

Though the drug studies were set up to have these tnf agents used in combination with Methotrexate (mtx), many patients do take tnf agents without mtx.
Certain tnf agents work better than others if mtx is not being taken. Speak to your rheumatologist if you are considering going off mtx.
Dr. Pierre Moeser
Dr. Pierre Moeser
Thank
Dr. EVAN Leibowitz
Internal Medicine - Rheumatology

In brief: YES

Approximately 1 in 3 RA patients do not take Methotrexate (mtx).
There are a significant number of patients who take anti-tnf drugs without mtx...And are doing well. Some are probably not as effective without mtx such as Remicade (infliximab) and humira. But there are patients on these without mtx who are doing well too.

In brief: YES

Approximately 1 in 3 RA patients do not take Methotrexate (mtx).
There are a significant number of patients who take anti-tnf drugs without mtx...And are doing well. Some are probably not as effective without mtx such as Remicade (infliximab) and humira. But there are patients on these without mtx who are doing well too.
Dr. EVAN Leibowitz
Dr. EVAN Leibowitz
Thank
Get help from a real doctor now
Dr. Jane Van Dis
Board Certified, Obstetrics & Gynecology
14 years in practice
47M people helped
Continue
108,000 doctors available
Read more answers from doctors