8 doctors weighed in:

Which are side effects of simvastatin for the cholesterol?

8 doctors weighed in
Dr. Milton Alvis, jr
Preventive Medicine
3 doctors agree

In brief: All Relatively Rare

Cholesterol (?$, but misleading): a fat molecule manufactured by every animal cell, building block of each cell membrane (enables membrane fluidity/movement without tearing), fundamental to survival of every animal cell.
Lipoproteins (proteins which transport all fats in the water outside cells) is the correct issue for artery disease (e.g. Ldl ?700 nmol/l, HDL ?45 µmol/l). Study: nusi.Org, lustig.

In brief: All Relatively Rare

Cholesterol (?$, but misleading): a fat molecule manufactured by every animal cell, building block of each cell membrane (enables membrane fluidity/movement without tearing), fundamental to survival of every animal cell.
Lipoproteins (proteins which transport all fats in the water outside cells) is the correct issue for artery disease (e.g. Ldl ?700 nmol/l, HDL ?45 µmol/l). Study: nusi.Org, lustig.
Thank
Dr. Gurmukh Singh
Pathology
3 doctors agree

In brief: Side effects

The commonest side effects are muscle pain and damage.
Rarely rhabdomyolysis, lysis if muscle cells may occur and is a serious issue. Other side effects include liver damage. Gastro-intestinal disorders like constipation, diarrhea, skin rashes, precipitation of diabetes mellitus and neurologic problems like memory loss.

In brief: Side effects

The commonest side effects are muscle pain and damage.
Rarely rhabdomyolysis, lysis if muscle cells may occur and is a serious issue. Other side effects include liver damage. Gastro-intestinal disorders like constipation, diarrhea, skin rashes, precipitation of diabetes mellitus and neurologic problems like memory loss.
Thank
Dr. James Underberg
Internal Medicine

In brief: Muscle Aches/others

Primary side effects of statins in general are muscular, either aches, or in more severe cases ( and less common) muscle breakdown (rhabdomyolysis) which can lead to kidney failure and can be life threatening.
Statins can also increase the risk of diabetes, primarily in those at risk for diabetes, and this does not seem to offset the benefits in those who qualify for statin therapy. See addtional.

In brief: Muscle Aches/others

Primary side effects of statins in general are muscular, either aches, or in more severe cases ( and less common) muscle breakdown (rhabdomyolysis) which can lead to kidney failure and can be life threatening.
Statins can also increase the risk of diabetes, primarily in those at risk for diabetes, and this does not seem to offset the benefits in those who qualify for statin therapy. See addtional.
Thank
1 comment
Dr. James Underberg
SImvastatin in general has several concerns, primarily around drug-drug interactions. When used with some blood pressure medications , other drugs used for cardiovascular conditions such as arrhythmias and in combination with drugs used for treating HIV and Hepatitis c, care should be taken to use the proper dose. As with any drug-drug interaction concerns, speaking to a trained, licensed pharmacist can by very important and helpful. Speak to you doctor also if you take other meds along with simvastatin.
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