Why are both a creatinine clearance test and a serum creatinine test done? Pain in the rear to collect.

See below. You are right, a collection of the 24 hour urine is cumbersome.It is possible to have a estimate of the GFR and creatinine clearance based on serum creatinine with a formula and tables which are easily available, which dose not require the urine collection. The 24 hour collection may be more accurate in extremes of weight etc and not necessary for most clinical scenarios.

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I'm wondering why are both a creatinine clearance test and a serum creatinine test done?

Creatinine clearance. People who want to find out their renal function will collect a 24 hour urine for creatinine clearance. The blood sample is used to calculate the clearance of creatinine in the urine as it will be sent off for a creatinine level. Without it, the clearance of creatinine could not be calculated. The result of the test give the actual glomerular filtration rate of the patient. Read more...

Why are a creatinine clearance test and a serum creatinine test done together?

To get proper result. Creatinine clearance testing procedure and what measured is fully answered in prior question. The serum creatinine must be drawn right after the 24 hour urine collection to calculate how much creatinine is in serum and compare it to the total creatinine in the urine collection, to get an accurate measurement of renal function. Read more...