2 doctors weighed in:
Particular mechanism that increases the gastrin level?
2 doctors weighed in

Dr. Charles Cattano
Internal Medicine - Gastroenterology
1 doctor agrees
In brief: Acid feedback loop
Gastrin is a hormone that responds to the amount of stomach acid produced--not enough acid causes gastrin levels to rise to stimulate acid production.
Gastrin is suppressed when acid levels are adequate in normal patients. However, in those with hypersecretory states like zollinger-ellison syndrome, gastrin is continually produced in high concentration resulting in excess acid, diarrhea, ulcers.

In brief: Acid feedback loop
Gastrin is a hormone that responds to the amount of stomach acid produced--not enough acid causes gastrin levels to rise to stimulate acid production.
Gastrin is suppressed when acid levels are adequate in normal patients. However, in those with hypersecretory states like zollinger-ellison syndrome, gastrin is continually produced in high concentration resulting in excess acid, diarrhea, ulcers.
Dr. Charles Cattano
Dr. Charles Cattano
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