Can a woman have a normal ca125 blood test and still have ovarian cancer?

Ovarian cancer. Yes. Only 85% of ovarian cancers have an elevated ca 12 at presentation. Therefore, 15 of every 100 women with a diagnosis of ovarian cancer have a ca 125 within the normal range. Ca 125 is not a diagnostic test. But is used to follow the progress of chemotherapy.
Yes. Ca 125 is not a good cancer marker. If elevate with a cancer, it may be used to monitor the progress of the tumor and effectiveness of treatment.
Possibly. Not usually but there are more accurate tests now , like the ova-1 and if I do a ca-125 i combine it with an he-4 blood test. If you are worried obviously you need to also have an ultrasound and possible further testing and your gyn can refer to to a gyn oncology surgeon- that type of doctor has additional training to deal with pre-cancer and cancer and to rule them in or out.
Yes. Ca 125 is not sensitive nor specific. Yes, some ovarian cancer do not produce ca 125- thus, ca -125 is only useful as a toold to monitor- for somebody who unfortunately has ovarian cancer and the ca 125 level is elevated.

Related Questions

I have a 2.8cm ovarian cyst. I have the brca1 mutated gene. My ca125 blood test came back normal. Could it still be early stage of ovarian cancer?

Rare. Ovarian cysts are of concern when over 5 cm. If the small cyst is not complex it is usually followed by ultrasound. Ca 125 has no diagnostic implication but is only of value for monitoring. Brca1 suggests the cyts should be followed. Read more...
Should seek Genetic. Genetic counseling is advised unless already done. Ca125 is not entirely reliable and a normal value does not exclude early ovarian cancer.. So you should either monitor the cystic lesion closely( imaging studies every 4-6 monthly) or consider removal of your ovaries if you have already completed your family. Good luck. Read more...

Does a ca125 blood test check for cancers other than ovarian cancer?

Yes. There are other cancers that will have a positive ca-125. They include cancer of the pancreas, stomach, esophagus, liver, breast, colon, or lung. Cancer of the lining of the abdominal cavity, and cancer of the fallopian tubes or lining of uterus. Read more...

Why is the ca-125 blood test to check for ovarian cancer not part of a woman's checkup?

Not useful. It is neither sensitive nor specific for ovarian cancer and is not useful as a screening test. If elevated at diagnosis of ovarian cancer, it is useful in following the progress of tumor and response to treatment. Read more...

Is it possible to have ovarian cancer and have a normal ca 125 blood test?

Yes. Ca125 can vary from person to person and can change under various circumstances not related to cancer. It is more useful as a way to track disease progression or treatment success. Read more...

Why is the ca-125 blood test for ovarian cancer not part of a yearly checkup?

Not beneficial. The ca125 test is not used for screening for ovarian cancer because it does not work in the general female population. The ca125 can be abnormal in situations without any cancer and most importantly using this test does not save any lives like in the case of maamograms for breast cancer. Read more...

I have all the symptoms of ovarian cancer. Had a blood test and it was negative and my scan turned out negative too. So what is the matter?

Ovarian cancer. More often than not, ovarian cancer does not have symptoms. If your scan and blood tests are negative, obviously one must consider other causes. If you separately list your symptoms here, we might be able to help. Even better might be a consult via HealthTap Prime or Healthtap Concierge. Whatever we can do to help. Good luck. Read more...

Any reliable blood test for ovarian cancer?

CA-125 test. The best blood test is a ca-125 but it is not totally specific. Other tests, like pelvic exam, and transvaginal ultrasound would be needed. The ultimate way to know is surgery to see if it is in fact, a tumor of something else. Read more...
NO. There is no good / reliable blood test for ovarian cancer as a screening test. However, if you have ovarian cancer , a cancer marker- ca-125, in majority times is elevated in ovarian cancer and this can be used to monitor response to treatment. Read more...
Non. The blood marker for ovarian cancer is CA 125. This represents a carbohydrate marker that is seen in ovarian cancer as well as inflammatory disorders involving the liver. FDA has determined that this marker can only be used for monitoring response one the diagnosis of ovarian cancer has been made. In treating ovarian cancer if this marker goes up or down it is a reflection of treatment response. Read more...

Any good easy blood test to screen for ovarian cancer yet?

Unfortunately No. Until now, there is no good way that we can use to screen ovarian cancer unfortunately, ..Not a blood work, not an imaging study- nothing is good and reliable enough to screen ovarian cancer. Please f/u woth your gynecologist regularly. Read more...
Not yet. The usual markers for cancer are useful for measuring the progress of tumors, but not of much use as screening tools. Read more...
No. Some may offer a ca-125 blood test as a screening for ovarian cancer. Unfortunately, while ca-125 is found in 80-90% of ovarian cancer patients, it is not very specific (meaning it is elevated in a number of conditions) and is not found in early cancers. It is better used as a method of following cancer treatment and progression, once it is diagnosed. Read more...

Can they detect ovarian cancer through a blood test?

Poorly. Some (not most) ovarian cancers make ca125 which can be assayed in the blood. There are so many false-positives and false-negatives that most physicians believe that the test should not be used routinely to screen every woman. Read more...
Backward. There is no screening test for ovca. However, if you have ovarian cancer, a ca-125 level may or may not be elevated. If it is, it may be one thing monitired for response. Getting ca-125, an expensive blood test of unproven value before knowing you have the cancer is inded backward, costly, non-specific and can led to unnecessary worry. Read more...