How to go about donating platelets by apheresis?

Platelet Donation. A platelet donor using apheresis must meet requirements for a regular blood donor and: 1) be at least 16 years old 2) be in good health 3) weigh at least 110 pounds 4) have a good vein 5) refrain from taking aspirin, or products containing Aspirin or feldene, (piroxicam) for 48 hours prior to donating. Always check with your local blood donation center first before going to donate.