2 doctors weighed in:

What are the cox-1 and cox-2 inhibitors? Are they pain blockers?

2 doctors weighed in
Dr. Rick Kirschner
General Practice
1 doctor agrees

In brief: No and Yes

Cox-1 (cyclooxygenase-1) is an enzyme that regulates prostaglandins, and is important for a healthy stomach lining and kidneys.
Inhibition turns this off, leading to gastrointestinal bleeding. Cox-2 (cyclooxygenase-2) is an enzyme that makes the prostaglandins which increase inflammation, pain and fever. So a cox-2 inhibitor is, in effect, a pain blocker.

In brief: No and Yes

Cox-1 (cyclooxygenase-1) is an enzyme that regulates prostaglandins, and is important for a healthy stomach lining and kidneys.
Inhibition turns this off, leading to gastrointestinal bleeding. Cox-2 (cyclooxygenase-2) is an enzyme that makes the prostaglandins which increase inflammation, pain and fever. So a cox-2 inhibitor is, in effect, a pain blocker.
Dr. Rick Kirschner
Dr. Rick Kirschner
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