Is there a lot of pain after testicular biopsy?

Not really. . Testicular biopsies should heal with a minimum of pain. There is very little tugging or manipulation of the spermatic cord, and there is no real chance of a nerve injury. The incision site should heal with few problems. Pains are sent home with a minimum of narcotic medication, if any. If there is a complication, such as wound infection or hematoma, these can cause some discomfort.