6 doctors weighed in:
What causes lupus to happen?
6 doctors weighed in

Dr. Thomas Namey
Internal Medicine - Rheumatology
4 doctors agree
In brief: NOT KNOWN...
No one knows the final "trigger-pull" that causes lupus.
We do know genetics play some role. We do know that hormones play a major role (reason for female dominance and females rarely getting sle before puberty). But why some with similar factors get disease is not known at present.

In brief: NOT KNOWN...
No one knows the final "trigger-pull" that causes lupus.
We do know genetics play some role. We do know that hormones play a major role (reason for female dominance and females rarely getting sle before puberty). But why some with similar factors get disease is not known at present.
Dr. Thomas Namey
Dr. Thomas Namey
Thank
Dr. Alfred Kim
Internal Medicine - Rheumatology
2 doctors agree
In brief: Genes, environment
This answer will change as we know more about lupus.
We believe that for a person to get lupus, from the limited genetic information we have now, about 10% is from known genetic causes and remaining 90% unknown genetic causes and environmental causes. Environmental causes are largely undefined but important. Think about this: only 30% of identical twins develop lupus together.

In brief: Genes, environment
This answer will change as we know more about lupus.
We believe that for a person to get lupus, from the limited genetic information we have now, about 10% is from known genetic causes and remaining 90% unknown genetic causes and environmental causes. Environmental causes are largely undefined but important. Think about this: only 30% of identical twins develop lupus together.
Dr. Alfred Kim
Dr. Alfred Kim
Thank
Read more answers from doctors