While men get these diseases as well, all of the following are 6-15x more common in females, and are autimmune: 1.
Ra, 2. Sle, 3. Scleroderma, 4. Mctd, 5. Polymyositis, 6. Sjogren's. All can be related to the presecne of estorgen, which is why they are uncommon in females before puberty. However, men with klinefelter's syndrome, who are xxy, have very high levels of estrogen and these diseases.
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