Supplementation. Vitamin d below 20 is in the deficient range it can cause sadness, dental discomfort, feeling fatigued, poor skin healing as well as easy pigmentation. You need a loading dose of vitamin d 50, 000 followed by supplementation of d3 daily. Most physicians start at about 2000-5000units daily. If you have GI problems, you may not absorb as well and many alternative physicians offer vitamin d shots.