5 doctors weighed in:
Why does untreated peripheral arterial disease lead to loss of leg?
5 doctors weighed in

Dr. Scott Bolhack
Wound care
2 doctors agree
In brief: PAD Leg Loss
Without the ability for blood to travel in the arteries to supply oxygen to the tissues of the distal leg, those tissues become at risk for tissue death.
With tissue death, there will be loss of limb.

In brief: PAD Leg Loss
Without the ability for blood to travel in the arteries to supply oxygen to the tissues of the distal leg, those tissues become at risk for tissue death.
With tissue death, there will be loss of limb.
Dr. Scott Bolhack
Dr. Scott Bolhack
Thank
Dr. Sendhil Subramanian
Radiology - Interventional
In brief: Untreated disease
The loss of a leg can occur if the PAD becomes very severe.
Usually PAD, begins with leg pain and cramping while walking or exercising. This can progress to pain while at rest. If it gets severe can result in cold feet, numbness, severe pain and burning. If it progresses further one can develop foot or toe ulcers which can get infected and develop gangrene and possible limb loss if untreated early

In brief: Untreated disease
The loss of a leg can occur if the PAD becomes very severe.
Usually PAD, begins with leg pain and cramping while walking or exercising. This can progress to pain while at rest. If it gets severe can result in cold feet, numbness, severe pain and burning. If it progresses further one can develop foot or toe ulcers which can get infected and develop gangrene and possible limb loss if untreated early
Dr. Sendhil Subramanian
Dr. Sendhil Subramanian
Thank
Dr. Jonathan Ellichman
Surgery - Vascular
In brief: Ischemia
The leg eventually dies and an infection takes over as bacteria live off the dead tissue.
Diabetics and smokers are at elevated risk.

In brief: Ischemia
The leg eventually dies and an infection takes over as bacteria live off the dead tissue.
Diabetics and smokers are at elevated risk.
Dr. Jonathan Ellichman
Dr. Jonathan Ellichman
Thank
Get help from a real doctor now
Dr. Umesh Patel
Board Certified, Internal Medicine - Cardiology
38 years in practice
1M people helped
Continue
108,000 doctors available
Read more answers from doctors