Stretch mark removal after or during weight loss. I hear it really cannot be done?

Can be tough to tx. I feel that it's hard to predict the response with stretch mark treatment. Various treatments can be used, depending on your skin type, & age and color of the stretch mark. These include topical treatment (primarily retinoids), pulsed dye laser, intense pulsed light. Microdermabrasion sometimes helps. Fractionated co2 laser can be done, but is a more aggressive treatment with downtime & more risk.