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Sudden shortness of breath which wakes me up in the sleep with hot chills and pounding heart beat.

Need pulmonary eval. Your symptoms, especially when combined with fever, indicate a primary pulmonary cause. I don't know what you mean by hot chills, but I am assuming you are shaking in a fever. As such, pneumonia will need to be ruled out. See your family doctor or go to the er if you run a fever over 101.5 degrees. It is possible that bacteria have gone into your blood stream, which is never desirable and are causing the hot chills. Read more...